Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463663 | 0.83 | MAPK1 (0.38) | MAPK1ALDH1A1PRKCA | |
| SCHEMBL2466001 | 0.81 | TDP1 (0.42) | MAPK1ALDH1A1LMNAHSD17B10TDP1 | |
| SCHEMBL9019756 | 0.79 | PRKCA (0.53) | ALDH1A1LMNAHSD17B10TDP1AR | |
| SCHEMBL9019825 | 0.78 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10TDP1PRKCA | |
| SCHEMBL11258229 | 0.78 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10TDP1PRKCA | |
| SCHEMBL9626733 | 0.77 | ALDH1A1 (0.43) | MAPK1ALDH1A1LMNAHSD17B10TDP1 | |
| SCHEMBL9019766 | 0.76 | TSHR (0.36) | ALDH1A1LMNAHSD17B10TDP1MEN1 | |
| SCHEMBL9019745 | 0.74 | ALDH1A1 (0.47) | ALDH1A1LMNAHSD17B10TDP1PRKCA | |
| SCHEMBL9463774 | 0.74 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10TDP1AR | |
| SCHEMBL9193268 | 0.74 | TSHR (0.34) | ALDH1A1LMNAHSD17B10TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225590-A | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0187297-B1 | ALKOXY METHYL ETHER AND ALKOXY METHYL ESTER DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0187297-A2 | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-07-16 | — | — | EP | disclosed |