Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463689 | 0.84 | HTR1A (0.52) | HTR1ADRD2HTR2ASLC6A2SLC6A3 | |
| SCHEMBL9464172 | 0.83 | HTR1A (0.51) | HTR1ADRD2HTR2ASLC6A2SLC6A3 | |
| SCHEMBL9463759 | 0.82 | HTR1A (0.50) | HTR1ADRD2HTR2ASLC6A2SLC6A3 | |
| SCHEMBL9465050 | 0.82 | HTR1A (0.55) | HTR1ADRD2HTR2ASLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL9464214 | 0.81 | HTR1A (0.49) | HTR1ADRD2HTR2ASLC6A2SLC6A3 | |
| SCHEMBL8948031 | 0.79 | HTR1A (0.49) | HTR1ADRD2HTR2ASLC6A2SLC6A3 | |
| SCHEMBL10394028 | 0.77 | DRD2 (0.62) | HTR1ADRD2HTR2ASLC6A2SLC6A3 | |
| SCHEMBL9463870 | 0.77 | HTR1A (0.53) | HTR1ASLC6A2SLC6A3TSHRMEN1 | |
| SCHEMBL10393591 | 0.76 | HTR1A (0.59) | HTR1ADRD2HTR2ASLC6A2SLC6A3 | |
| SCHEMBL4675791 | 0.74 | GRIN1 (0.71) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182278-A | Arterial hypotensive agents | ADIR ET COMPAGNIE (FR) | 1993-01-26 | — | — | US | disclosed |