Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.72 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.72 |
| ▸ | ADRB3 | P13945 | 11/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8758959 | 0.85 | ADRB2 (0.67) | ADRB2ADRB1ADRB3NPC1RAB9A | |
| SCHEMBL17459869 | 0.81 | CES2 (0.57) | ADRB2ADRB1ADRB3NPC1RAB9A | |
| SCHEMBL29934134 | 0.81 | CES2 (0.57) | ADRB2ADRB1ADRB3NPC1RAB9A | |
| SCHEMBL9463857 | 0.80 | MAPK1 (0.56) | ADRB2ADRB1ADRB3NPC1RAB9A | |
| SCHEMBL9463929 | 0.80 | ALDH1A1 (0.52) | ADRB2ADRB1ADRB3RAB9AALDH1A1 | |
| SCHEMBL9463407 | 0.80 | ADRB2 (0.51) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL641903 | 0.79 | POLB (0.62) | ADRB2ADRB1ADRB3NPC1TDP1 | |
| SCHEMBL31237097 | 0.79 | POLB (0.62) | ADRB2ADRB1ADRB3NPC1TDP1 | |
| SCHEMBL2331478 | 0.79 | CES2 (0.55) | ADRB2ADRB1ADRB3NPC1RAB9A | |
| SCHEMBL8723109 | 0.79 | ADRB2 (0.54) | ADRB2ADRB1ADRB3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225590-A | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0187297-B1 | ALKOXY METHYL ETHER AND ALKOXY METHYL ESTER DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0187297-A2 | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-07-16 | — | — | EP | disclosed |