Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4931181 | 0.77 | CYP1A2 (0.55) | CYP1A2CYP1B1KMT2AMEN1KDM4E | |
| SCHEMBL29590196 | 0.77 | KDM4E (0.62) | PDE4DKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9463889 | 0.71 | ALDH2 (0.60) | KMT2AMEN1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL30637608 | 0.70 | ESR1 (0.54) | PDE4DCYP1A2KMT2AMEN1KDM4E | |
| SCHEMBL9464056 | 0.70 | MAOA (0.47) | PDE4DCYP1A2KMT2AMEN1KDM4E | |
| SCHEMBL9626684 | 0.67 | PDE4D (0.41) | PDE4DLMNAMAPT | |
| SCHEMBL22135594 | 0.66 | DPP4 (0.56) | CYP1A2CYP1B1KMT2AKDM4EMAOB | |
| SCHEMBL19313330 | 0.66 | DPP4 (0.64) | CYP1A2CYP1B1KMT2AKDM4EMAOB | |
| SCHEMBL19313331 | 0.66 | DPP4 (0.64) | CYP1A2CYP1B1KMT2AKDM4EMAOB | |
| Isojacareubin SCHEMBL29808479 | 0.64 | PDE5A (0.59) | PDE4DKMT2AMEN1KDM4EMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216176-A | 7-alkoxycoumarins, dihydropsoralens, and benzodipyranones as photo-activated therapeutic agents and inhibitors of epidermal growth factor | LEHIGH UNIVERSITY (US) | 1993-06-01 | — | — | US | disclosed |