Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464078 | 1.00 | LMNA (0.43) | LMNAKDM4EALDH1A1HPGDPKM | |
| SCHEMBL9463675 | 0.78 | TP53 (0.50) | LMNAKDM4EALDH1A1HPGDPKM | |
| SCHEMBL9463672 | 0.78 | TP53 (0.50) | LMNAKDM4EALDH1A1HPGDPKM | |
| SCHEMBL9463869 | 0.77 | TP53 (0.52) | LMNAKDM4EALDH1A1HPGDPKM | |
| SCHEMBL9463846 | 0.77 | TSHR (0.43) | LMNAKDM4EALDH1A1HPGDPKM | |
| SCHEMBL9463983 | 0.77 | TSHR (0.43) | LMNAKDM4EALDH1A1HPGDPKM | |
| SCHEMBL1027286 | 0.76 | ALDH1A1 (0.50) | LMNAKDM4EALDH1A1HPGDPKM | |
| SCHEMBL9463921 | 0.76 | LMNA (0.51) | LMNAKDM4EALDH1A1HPGDPKM | |
| SCHEMBL9463915 | 0.76 | LMNA (0.51) | LMNAKDM4EALDH1A1HPGDPKM | |
| SCHEMBL9463696 | 0.73 | PKM (0.40) | LMNAKDM4EALDH1A1HPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182278-A | Arterial hypotensive agents | ADIR ET COMPAGNIE (FR) | 1993-01-26 | — | — | US | disclosed |
| US-5132305-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-07-21 | — | — | US | disclosed |