Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464220 | 0.99 | HTR1A (0.60) | HTR1ATP53MAPK1SLC6A2SLC6A4 | |
| SCHEMBL9464567 | 0.91 | HTR1A (0.62) | HTR1ATP53MAPK1SLC6A2SLC6A4 | |
| SCHEMBL9463688 | 0.90 | HTR1A (0.59) | HTR1ATP53MAPK1SLC6A2SLC6A4 | |
| SCHEMBL10393710 | 0.85 | HTR1A (0.67) | HTR1ASLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL9463870 | 0.84 | HTR1A (0.53) | HTR1ATP53MAPK1SLC6A2SLC6A4 | |
| SCHEMBL10392906 | 0.83 | HTR1A (0.62) | HTR1AMAPK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9464160 | 0.81 | KDM4E (0.51) | HTR1ASLC6A2SLC6A4SLC6A3PKM | |
| SCHEMBL10393719 | 0.81 | HTR1A (0.51) | HTR1AMAPK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10394035 | 0.80 | HTR1A (0.62) | HTR1ASLC6A2SLC6A4SLC6A3POLB | |
| SCHEMBL8870844 | 0.80 | SIGMAR1 (0.66) | HTR1ATP53TSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132305-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-07-21 | — | — | US | claimed |
| US-5182278-A | Arterial hypotensive agents | ADIR ET COMPAGNIE (FR) | 1993-01-26 | — | — | US | disclosed |
| US-5132305-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-07-21 | — | — | US | disclosed |