Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | JAK2 | O60674 | 1/20 | 0.85 |
| ▸ | TYK2 | P29597 | 1/20 | 0.85 |
| ▸ | GAA | P10253 | 2/20 | 0.81 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | STAT3 | P40763 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.68 |
| ▸ | CA9 | Q16790 | 1/20 | 0.68 |
| ▸ | NAMPT | P43490 | 3/20 | 0.66 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL164882 | 0.92 | JAK2 (1.00) | HTTJAK2TYK2GAAKCNK3 | |
| N-Phenylbenzamide SCHEMBL28666916 | 0.90 | HTT (0.82) | HTTJAK2TYK2GAAKCNK3 | |
| SCHEMBL1898755 | 0.90 | GAA (0.91) | HTTJAK2TYK2GAAKCNK3 | |
| SCHEMBL19242053 | 0.90 | GAA (1.00) | HTTJAK2TYK2GAAKCNK3 | |
| Methyl Alcohol SCHEMBL28281305 | 0.86 | GAA (0.84) | HTTJAK2TYK2GAAKCNK3 | |
| SCHEMBL29393952 | 0.85 | JAK2 (0.86) | HTTJAK2TYK2GAAKCNK3 | |
| SCHEMBL29013035 | 0.85 | POLB (1.00) | HTTJAK2TYK2GAASMN1; SMN2 | |
| SCHEMBL6448103 | 0.85 | POLB (0.81) | HTTJAK2TYK2GAAKCNK3 | |
| SCHEMBL5466412 | 0.85 | JAK2 (0.86) | HTTJAK2TYK2GAAKCNK3 | |
| SCHEMBL14716526 | 0.85 | KDM4E (1.00) | HTTJAK2TYK2GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104114555-B | Pyrazolopyrimidine derivatives, process for their preparation and their therapeutic use | 赛诺菲 | 2017-09-01 | — | — | CN | claimed |
| CN-104114555-A | Pyrazolopyrimidine derivatives, process for their preparation and their therapeutic use | SANOFI SA | 2014-10-22 | — | — | CN | claimed |
| US-6605720-B1 | Process for making spirolactone compounds | MERCK & CO., INC. | 2003-08-12 | — | — | US | claimed |
| US-20030144515-A1 | PROCESS FOR MAKING SPIROLACTONE COMPOUNDS | MERCK SHARP & DOHME LLC | 2003-07-31 | — | — | US | claimed |
| US-5665680-A | Method for increasing yield of soybean by inhibition of gibberellin biosynthesis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-09-09 | — | — | US | claimed |
| EP-0048998-B1 | ISONICOTINANILIDE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND PLANT GROWTH REGULATOR CONTAINING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1985-01-09 | — | — | EP | claimed |
| EP-0048998-A2 | Isonicotinanilide derivatives, process for preparing the same and plant growth regulator containing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-04-07 | — | — | EP | claimed |
| JP-9000071-A | — | — | None | — | — | JP | disclosed |
| JP-9000070-A | — | — | None | — | — | JP | disclosed |
| JP-9000069-A | — | — | None | — | — | JP | disclosed |
| JP-9000068-A | — | — | None | — | — | JP | disclosed |
| JP-55139306-A | — | — | None | — | — | JP | disclosed |
| JP-9098666-A | — | — | None | — | — | JP | disclosed |
| US-4377407-A | Isonicotinanilide derivatives, plant growth regulating compositions and use | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1983-03-22 | — | — | US | disclosed |
| EP-0048998-A2 | Isonicotinanilide derivatives, process for preparing the same and plant growth regulator containing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-04-07 | — | — | EP | disclosed |
| EP-0048998-A2 | Isonicotinanilide derivatives, process for preparing the same and plant growth regulator containing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-04-07 | — | — | EP | disclosed |
| EP-0048998-A2 | Isonicotinanilide derivatives, process for preparing the same and plant growth regulator containing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-04-07 | — | — | EP | disclosed |
| US-4243666-A | HYPOTENSIVE AGENTS | PFIZER INC. (US) | 1981-01-06 | — | — | US | disclosed |
| JP-S55139306-A | PLANT GROWTH REGULATOR | CHUGAI PHARMACEUT CO LTD | 1980-10-31 | — | — | JP | disclosed |
| US-4069224-A | N-(PYRIDYLALKYL)BENZAMIDES, IMPROVE PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144515-A1 | PROCESS FOR MAKING SPIROLACTONE COMPOUNDS | HSD17B7, PKD1, REN | HTT 3602/4885JAK2 2651/4885TYK2 3526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.