Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | AR | P10275 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.49 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MPI | P34949 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | COMT | P21964 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682189 | 0.84 | SLC5A1 (0.53) | LMNASMN1; SMN2ARMEN1KMT2A | |
| SCHEMBL21274894 | 0.84 | ALDH1A1 (0.58) | LMNASMN1; SMN2ARSLC5A1SLC5A2 | |
| SCHEMBL3633161 | 0.84 | ALDH1A1 (0.50) | LMNASMN1; SMN2ARMEN1KMT2A | |
| SCHEMBL13313003 | 0.82 | LMNA (0.66) | LMNASMN1; SMN2ARMEN1KMT2A | |
| SCHEMBL26100801 | 0.79 | LMNA (0.62) | LMNASMN1; SMN2ARMEN1KMT2A | |
| SCHEMBL22197860 | 0.79 | MEN1 (0.62) | LMNASMN1; SMN2ARMEN1KMT2A | |
| SCHEMBL4230856 | 0.79 | LMNA (0.62) | LMNASMN1; SMN2ARMEN1KMT2A | |
| SCHEMBL17156328 | 0.79 | SLC5A2 (0.52) | LMNASMN1; SMN2ARSLC5A1SLC5A2 | |
| SCHEMBL1774454 | 0.79 | LMNA (0.66) | LMNASMN1; SMN2ARMEN1KMT2A | |
| SCHEMBL21274861 | 0.78 | PTGS1 (0.45) | LMNASMN1; SMN2ARMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210169-A | Polyisocyanates blocked with pyrazole or indazole derivatives, polyamine hardener, good reactivity and shelf stability | CIBA-GEIGY CORPORATION (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0500495-A2 | Thermosetting composition | CIBA-GEIGY AG (CH) | 1992-08-26 | — | — | EP | disclosed |