Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312298 | 0.92 | SRD5A2 (0.53) | TP53TSHRSRD5A2MAPK1MAPT | |
| SCHEMBL9859728 | 0.87 | VCAM1 (0.57) | SRD5A2MAPK1MAPTTDP1KDM4E | |
| SCHEMBL9464836 | 0.85 | LMNA (0.57) | SRD5A2MAPK1MAPTKDM4EHTT | |
| SCHEMBL8962986 | 0.85 | L3MBTL1 (0.52) | SRD5A2MAPK1MAPTTDP1KDM4E | |
| SCHEMBL10609508 | 0.78 | SRD5A2 (0.55) | TSHRSRD5A2MAPK1MAPTTDP1 | |
| SCHEMBL9065412 | 0.78 | SRD5A2 (0.80) | TSHRSRD5A2MAPK1MAPTKDM4E | |
| SCHEMBL51827 | 0.78 | SRD5A2 (0.80) | TSHRSRD5A2MAPK1MAPTKDM4E | |
| SCHEMBL1681512 | 0.78 | SRD5A2 (0.80) | TSHRSRD5A2MAPK1MAPTKDM4E | |
| SCHEMBL10697158 | 0.78 | SRD5A2 (0.80) | TSHRSRD5A2MAPK1MAPTKDM4E | |
| SCHEMBL17025499 | 0.78 | MAPK1 (0.50) | TSHRSRD5A2MAPK1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204453-A | Process for the preparation of 1:2 metal complex azo compounds by carrying out diazotization and coupling in the presence of a metal donor | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0241414-B1 | PROCESS FOR THE PREPARATION OF 1:2 METAL COMPLEX AZO DYES | CIBA-GEIGY AG (CH) | 1991-05-08 | — | — | EP | disclosed |
| US-4997921-A | Substituted phenylazosulfoindole dyes | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4954563-A | Polyamide dye | CIBA-GEIGY CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0121495-B1 | MONOAZO DYESTUFFS, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1986-12-17 | — | — | EP | disclosed |
| EP-0121495-A1 | Monoazo dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-10-10 | — | — | EP | disclosed |