SCHEMBL9464671

SCHEMBL9464671

CC(Br)OC(=O)Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
ATM Q13315 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ELANE P08246 2/20 0.42
MAPT P10636 1/20 0.42
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
MTNR1A P48039 4/20 0.41
MTNR1B P49286 4/20 0.41
USP2 O75604 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
ALOX15 P16050 2/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL8717860 0.84 TSHR (0.48) ALDH1A1ATML3MBTL1ELANEMAPT
SCHEMBL1792881 0.84 TSHR (0.48) ALDH1A1ATML3MBTL1ELANEMAPT
SCHEMBL16353853 0.81 ALDH1A1 (0.42) ALDH1A1ATML3MBTL1ELANEMAPT
SCHEMBL4492405 0.81 ALOX15 (0.43) ALDH1A1ATML3MBTL1ELANEMAPT
SCHEMBL4740194 0.81 ALDH1A1 (0.42) ALDH1A1ATML3MBTL1ELANEMAPT
SCHEMBL6895672 0.81 ALDH1A1 (0.42) ALDH1A1ATML3MBTL1ELANEMAPT
SCHEMBL18671080 0.80 ALDH1A1 (0.40) ALDH1A1ATML3MBTL1ELANEMAPT
SCHEMBL8846903 0.79 HCAR2 (0.53) ALDH1A1ATML3MBTL1ELANEMAPT
SCHEMBL17317282 0.79 MTNR1A (0.47) ALDH1A1ATML3MBTL1ELANEMAPT
SCHEMBL2988210 0.78 ALDH1A1 (0.40) ALDH1A1ATML3MBTL1ELANEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5202454-A Catalytically reacting alpha-chlorinated carbonate derivatives with anhydrous brominated compound SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1993-04-13 US disclosed
US-4808745-A Process for the preparation of 1-bromoethyl hydrocarbonyl carbonates and new 1-bromoethyl hydrocarbonyl carbonates SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1989-02-28 US disclosed
US-4697032-A Process for the preparation of 1-bromoethyl hydrocarbonyl carbonates and new 1-bromoethyl hydrocarbonyl carbonates SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1987-09-29 US disclosed