SCHEMBL9464673

SCHEMBL9464673

CC(=O)Nc1cc(O)cc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 3/20 0.55
POLB P06746 3/20 0.50
CASP6 P55212 1/20 0.50
NQO2 P16083 1/20 0.48
KDM4E B2RXH2 5/20 0.48
ALDH1A1 P00352 4/20 0.48
GAA P10253 2/20 0.48
GLA P06280 1/20 0.48
RXFP1 Q9HBX9 1/20 0.47
HPGD P15428 3/20 0.46
LMNA P02545 2/20 0.46
CYP1A2 P05177 1/20 0.46
MAOA P21397 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MAPT P10636 2/20 0.46
PKM P14618 1/20 0.46
APOBEC3A P31941 1/20 0.45
GFER P55789 1/20 0.45
HDAC1 Q13547 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10040374 0.84 CDC25B (0.50) CDC25BPOLBNQO2KDM4EALDH1A1
SCHEMBL6691636 0.83 POLB (0.57) POLBCASP6KDM4EALDH1A1GAA
SCHEMBL6746219 0.82 ALDH1A1 (0.59) POLBCASP6KDM4EALDH1A1GAA
SCHEMBL23715982 0.82 CDC25B (0.51) CDC25BNQO2KDM4EALDH1A1GAA
SCHEMBL26639942 0.82 CDC25B (0.51) CDC25BPOLBNQO2ALDH1A1HPGD
SCHEMBL14503713 0.81 POLB (0.49) POLBCASP6KDM4EALDH1A1GAA
SCHEMBL9156203 0.81 CASP6 (0.64) POLBCASP6KDM4EALDH1A1GAA
SCHEMBL19422040 0.78 NQO2 (0.55) CDC25BNQO2KDM4EALDH1A1GAA
SCHEMBL29514721 0.78 KDM4E (0.69) POLBCASP6KDM4EALDH1A1GAA
SCHEMBL357522 0.78 KDM4E (0.69) POLBCASP6KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5204453-A Process for the preparation of 1:2 metal complex azo compounds by carrying out diazotization and coupling in the presence of a metal donor CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
EP-0278910-B1 HEAVY METAL COMPLEX DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1992-01-22 EP disclosed
EP-0241414-B1 PROCESS FOR THE PREPARATION OF 1:2 METAL COMPLEX AZO DYES CIBA-GEIGY AG (CH) 1991-05-08 EP disclosed
US-5001227-A Fibre-reactive 1:1 chromium complex azo or azomethine dyes having a bidentate chelating group and a monofunctional neutral ligand CIBA-GEIGY CORPORATION (US) 1991-03-19 US disclosed
US-4990598-A Colorfastness CIBA-GEIGY CORPORATION, A CORP. OF NEW YORK 1991-02-05 US disclosed
US-4960870-A DYEING WOOL, POLYAMIDES; FIBER REACTIVE DYES CIBA-GEIGY CORPORATION (US) 1990-10-02 US disclosed
EP-0142104-B1 FIBRE-REACTIVE CHROMIUM COMPLEXES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1990-01-03 EP disclosed
US-4874391-A USING WATER SOLUBLE COPPER COMPLEX AZO DYE, LIGHT STABILIZER AND ANTIOXIDANT CIBA-GEIGY CORPORATION (US) 1989-10-17 US disclosed
EP-0144776-B1 FIBRE-REACTIVE CHROMIUM COMPLEXES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1989-10-11 EP disclosed
EP-0141416-B1 FIBRE-REACTIVE CHROMIUM COMPLEXES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1989-08-16 EP disclosed
US-4723001-A Fibre-reactive chromium complexes and their preparation and use CIBA-GEIGY CORPORATION (US) 1988-02-02 US disclosed
US-4704133-A FIBER-REACTIVE CIBA-GEIGY CORPORATION (US) 1987-11-03 US disclosed
EP-0241414-A2 Process for the preparation of 1:2 metal complex azo dyes CIBA-GEIGY AG (CH) 1987-10-14 EP disclosed
US-4680385-A Metal dye complexes containing an azo or azomethine dye and a colorless ligand with the C═N--N═C group CIBA-GEIGY CORPORATION (US) 1987-07-14 US disclosed
US-4678851-A FIBER-RACTIVE CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed
EP-0185611-A1 Process for the photochemical stabilisation of synthetic fibrous materials containing polyamide fibres CIBA-GEIGY AG (CH) 1986-06-25 EP disclosed
EP-0159962-A2 Fibre-reactive chromium or cobalt complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-10-30 EP disclosed
EP-0144776-A2 Fibre-reactive chromium complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-06-19 EP disclosed
EP-0142104-A2 Fibre-reactive chromium complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-05-22 EP disclosed
EP-0141416-A2 Fibre-reactive chromium complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-05-15 EP disclosed