Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464813 | 0.96 | AVPR1B (0.46) | CETPMAPTAVPR1BLTA4HSLC2A1 | |
| SCHEMBL9465027 | 0.90 | MAPT (0.54) | MAPTLTA4HALDH1A1POLB | |
| SCHEMBL9465413 | 0.89 | MEN1 (0.52) | MAPTSLC2A1ADRA1AHRH1ADRA1B | |
| SCHEMBL9465745 | 0.87 | SLC2A1 (0.47) | MAPTAVPR1BSLC2A1ALDH1A1HSD17B10 | |
| SCHEMBL9465695 | 0.85 | MEN1 (0.49) | MAPTAVPR1BSLC2A1ADRA1AHRH1 | |
| SCHEMBL9465008 | 0.83 | MAPT (0.47) | MAPTAVPR1BSLC2A1ADRA1AHRH1 | |
| SCHEMBL9472384 | 0.81 | LTA4H (0.44) | MAPTLTA4HALDH1A1HSD17B10MEN1 | |
| SCHEMBL9465061 | 0.81 | CYP1A2 (0.51) | MAPTALDH1A1HSD17B10LMNAMEN1 | |
| SCHEMBL9464725 | 0.81 | CETP (0.46) | CETPMAPTSLC2A1ADRA1AHRH1 | |
| SCHEMBL9465249 | 0.80 | MAPT (0.49) | MAPTAVPR1BSLC2A1ADRA1AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |