Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465413 | 0.96 | MEN1 (0.52) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9465027 | 0.92 | MAPT (0.54) | MAPTSMN1; SMN2TSHRALDH1A1GAA | |
| SCHEMBL9465008 | 0.90 | MAPT (0.47) | MEN1KMT2AMAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL9464813 | 0.89 | AVPR1B (0.46) | MAPTSMN1; SMN2NPC1RAB9AADRA1A | |
| SCHEMBL9465745 | 0.85 | SLC2A1 (0.47) | MEN1KMT2AMAPTNPC1CYP1A2 | |
| SCHEMBL9464732 | 0.85 | CETP (0.47) | MEN1KMT2AMAPTCYP1A2ALDH1A1 | |
| SCHEMBL9464761 | 0.83 | TSHR (0.45) | MEN1KMT2AMAPTSMN1; SMN2TSHR | |
| SCHEMBL9464546 | 0.83 | MAPT (0.47) | KMT2AMAPTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL9465249 | 0.83 | MAPT (0.49) | MEN1KMT2AMAPTSMN1; SMN2ADRA1A | |
| SCHEMBL9464655 | 0.83 | AVPR1B (0.47) | MEN1KMT2AMAPTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |