Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464732 | 0.96 | CETP (0.47) | AVPR1BADRA1AHRH1ADRA1BHRH3 | |
| SCHEMBL9465027 | 0.90 | MAPT (0.54) | MAPTLTA4HSMN1; SMN2POLB | |
| SCHEMBL9465695 | 0.89 | MEN1 (0.49) | AVPR1BADRA1AHRH1ADRA1BMAPT | |
| SCHEMBL9465008 | 0.87 | MAPT (0.47) | AVPR1BADRA1AHRH1ADRA1BHRH3 | |
| SCHEMBL9465413 | 0.85 | MEN1 (0.52) | ADRA1AHRH1ADRA1BMAPTLMNA | |
| SCHEMBL9465745 | 0.83 | SLC2A1 (0.47) | AVPR1BMAPTSLC2A1NPC1RAB9A | |
| SCHEMBL9464761 | 0.81 | TSHR (0.45) | MAPTSMN1; SMN2TDP1POLB | |
| SCHEMBL9464809 | 0.81 | MEN1 (0.43) | AVPR1BADRA1AHRH1ADRA1BHRH3 | |
| SCHEMBL9464546 | 0.80 | MAPT (0.47) | AVPR1BMAPTSMN1; SMN2 | |
| SCHEMBL9465249 | 0.80 | MAPT (0.49) | AVPR1BADRA1AHRH1ADRA1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |