Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464784 | 0.80 | MCHR1 (0.41) | POLBNPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL9464943 | 0.79 | HRH4 (0.41) | KMT2AEGFRTUBB4ATUBBTUBA3C | |
| SCHEMBL9464694 | 0.78 | ALDH1A1 (0.47) | POLBHTTKMT2ACYP2D6APAF1 | |
| SCHEMBL9464805 | 0.77 | KDM5B (0.35) | L3MBTL1EGFRTUBB4ATUBBTUBA3C | |
| SCHEMBL9464791 | 0.76 | ALDH1A1 (0.45) | KMT2ASMN1; SMN2FGFR1SRCCYP2D6 | |
| SCHEMBL9464915 | 0.76 | ALDH1A1 (0.45) | KMT2ASMN1; SMN2FGFR1SRCCYP2D6 | |
| SCHEMBL9464936 | 0.69 | HRH4 (0.42) | L3MBTL1KDM5BCYP2D6NSD2MAPT | |
| SCHEMBL9464781 | 0.68 | DPP4 (0.39) | POLBNPC1RAB9AL3MBTL1KDM5B | |
| SCHEMBL9464688 | 0.66 | LMNA (0.37) | POLBNPC1RAB9AHTTKMT2A | |
| SCHEMBL9465183 | 0.65 | ALDH1A1 (0.43) | HTTKMT2ASMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |