Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 6/20 | 0.40 |
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464694 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HTTHPGDHSD17B10GAA | |
| SCHEMBL9464969 | 0.84 | TSHR (0.46) | ALDH1A1GAATP53SMN1; SMN2TSHR | |
| SCHEMBL9464791 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL9464915 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HPGDHSD17B10GAASMN1; SMN2 | |
| SCHEMBL9464667 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HTTKDM4EHPGDHSD17B10 | |
| SCHEMBL9465176 | 0.80 | PRKDC (0.40) | ALDH1A1HTTKDM4EHPGDHSD17B10 | |
| SCHEMBL9464867 | 0.80 | ADORA2A (0.46) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL9464852 | 0.78 | AVPR1B (0.53) | ALDH1A1MAPTSMN1; SMN2SIGMAR1MEN1 | |
| SCHEMBL9465068 | 0.78 | LMNA (0.50) | ALDH1A1HTTKDM4EHPGDHSD17B10 | |
| SCHEMBL9464784 | 0.78 | MCHR1 (0.41) | ALDH1A1HTTHSD17B10L3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |