Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ACP1 | P24666 | 2/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465027 | 0.88 | MAPT (0.54) | TSHRALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL9465008 | 0.83 | MAPT (0.47) | TSHRALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL9465695 | 0.83 | MEN1 (0.49) | TSHRALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL9465413 | 0.81 | MEN1 (0.52) | TSHRALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL9464710 | 0.81 | ALDH1A1 (0.45) | TSHRALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL9465745 | 0.81 | SLC2A1 (0.47) | TSHRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9464655 | 0.81 | AVPR1B (0.47) | TSHRALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL9464546 | 0.81 | MAPT (0.47) | TSHRALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL9464813 | 0.81 | AVPR1B (0.46) | SMN1; SMN2MAPTPOLBTDP1 | |
| SCHEMBL9465081 | 0.81 | MAPT (0.45) | TSHRALDH1A1SMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |