Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465550 | 0.98 | HDAC1 (0.49) | ALDH1A1MAPK1FDPSHDAC1HDAC2 | |
| SCHEMBL9125570 | 0.86 | CA2 (0.57) | ALDH1A1MAPK1FDPSHDAC1HDAC2 | |
| SCHEMBL420011 | 0.79 | ALDH1A1 (0.78) | ALDH1A1MAPK1HDAC1HDAC2HDAC3 | |
| SCHEMBL5167895 | 0.77 | ALDH1A1 (0.74) | ALDH1A1MAPK1HDAC1HDAC2HDAC3 | |
| SCHEMBL5169003 | 0.77 | ALDH1A1 (0.74) | ALDH1A1MAPK1HDAC1HDAC2HDAC3 | |
| SCHEMBL24497111 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPK1FDPSHDAC1HDAC2 | |
| SCHEMBL21102978 | 0.77 | MTNR1A (0.51) | ALDH1A1MAPK1MTNR1AMTNR1BTHRB | |
| SCHEMBL9125717 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPK1FDPSHDAC1HDAC2 | |
| SCHEMBL6345235 | 0.76 | CA2 (0.68) | ALDH1A1MAPK1FDPSCA2MTNR1A | |
| SCHEMBL24497119 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPK1FDPSHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412110-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 1993-07-07 | — | — | EP | disclosed |
| US-5206229-A | Inhibit cell proliferation, antiinflammatory, treating imbalance of immune system | LEO PHARMACEUTICAL PRODUCTS LTD (DK) | 1993-04-27 | — | — | US | disclosed |
| EP-0412110-A1 | NOVEL VITAMIN D ANALOGUES. | LEO PHARM PROD LTD (DK) | 1991-02-13 | — | — | EP | disclosed |
| WO-1989010351-A1 | NOVEL VITAMIN D ANALOGUES | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LØVENS KEMIS (DK) | 1989-11-02 | — | — | WO | disclosed |