Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | THRA | P10827 | 5/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | ACR | P10323 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9466115 | 0.96 | THRB (0.46) | THRBMAPTSMN1; SMN2THRAKMT2A | |
| SCHEMBL9465854 | 0.91 | MAPT (0.40) | THRBMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL9466635 | 0.90 | LSS (0.38) | MAPTSMN1; SMN2PRSS1ACRKMT2A | |
| SCHEMBL9465609 | 0.90 | CTSK (0.37) | THRBMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL9465980 | 0.90 | CYP2C9 (0.37) | MAPTSMN1; SMN2PRSS1ACRKMT2A | |
| SCHEMBL9465202 | 0.89 | HDAC3 (0.38) | SMN1; SMN2PRSS1ACRNPC1LMNA | |
| SCHEMBL9467383 | 0.88 | MGLL (0.39) | MAPTSMN1; SMN2PRSS1ACRKMT2A | |
| SCHEMBL9465392 | 0.86 | TDP1 (0.34) | MAPTSMN1; SMN2PRSS1ACRKMT2A | |
| SCHEMBL9466004 | 0.83 | HTT (0.36) | THRBMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9465164 | 0.82 | HPGD (0.34) | KMT2ACYP1A2CYP3A4CYP2C19ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204018-A | LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1993-04-20 | — | — | US | disclosed |