Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357090 | 0.83 | NISCH (0.43) | MEN1KMT2ASMN1; SMN2GPR119GAA | |
| SCHEMBL10815443 | 0.71 | PDE3B (0.52) | ALDH1A1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL8866090 | 0.70 | GPR119 (0.47) | ALDH1A1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL8477694 | 0.69 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL11399417 | 0.68 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL8865871 | 0.66 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL6541516 | 0.66 | BRPF1 (0.54) | ALDH1A1MEN1KMT2APOLBTSHR | |
| SCHEMBL4215079 | 0.66 | MAOB (0.43) | ALDH1A1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL11529134 | 0.63 | PDE4A (0.51) | ALDH1A1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL6207998 | 0.63 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |