Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458086 | 0.76 | MAPK1 (0.46) | KLK7HSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL14424338 | 0.75 | ALDH1A1 (0.60) | HSD17B10ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL15770056 | 0.72 | ALDH1A1 (0.56) | HSD17B10ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL6999570 | 0.72 | KEAP1 (0.45) | KLK7HSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL28660408 | 0.71 | TTR (0.46) | MYCHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL29114348 | 0.70 | HSD17B10 (0.61) | MYCHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL7181506 | 0.69 | MEN1 (0.68) | HSD17B10ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL23499965 | 0.69 | KDM4E (0.49) | HSD17B10ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL2267128 | 0.69 | LDHA (0.51) | MYCHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL1059869 | 0.69 | ALDH1A1 (0.56) | MYCHSD17B10ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5241107-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1993-08-31 | — | — | US | disclosed |