Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18022101 | 0.82 | CA2 (0.33) | — | |
| SCHEMBL27491727 | 0.81 | TSHR (0.39) | LMNADNM1SMPD1OPRM1FDPS | |
| SCHEMBL27491046 | 0.81 | TSHR (0.39) | LMNADNM1SMPD1OPRM1FDPS | |
| SCHEMBL14716894 | 0.80 | CA2 (0.33) | — | |
| SCHEMBL14715814 | 0.80 | CA2 (0.33) | — | |
| SCHEMBL17442138 | 0.79 | OPRM1 (0.36) | LMNADNM1SMPD1OPRM1FDPS | |
| SCHEMBL12371522 | 0.78 | ZDHHC7 (0.37) | LMNADNM1SMPD1OPRM1TSHR | |
| SCHEMBL3897652 | 0.77 | FFAR1 (0.34) | LMNADNM1SMPD1OPRM1FDPS | |
| SCHEMBL20477537 | 0.77 | LMNA (0.33) | LMNADNM1SMPD1OPRM1FDPS | |
| SCHEMBL3897647 | 0.77 | FFAR1 (0.34) | LMNADNM1SMPD1OPRM1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412110-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 1993-07-07 | — | — | EP | disclosed |
| US-5206229-A | Inhibit cell proliferation, antiinflammatory, treating imbalance of immune system | LEO PHARMACEUTICAL PRODUCTS LTD (DK) | 1993-04-27 | — | — | US | disclosed |
| EP-0412110-A1 | NOVEL VITAMIN D ANALOGUES. | LEO PHARM PROD LTD (DK) | 1991-02-13 | — | — | EP | disclosed |
| WO-1989010351-A1 | NOVEL VITAMIN D ANALOGUES | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LØVENS KEMIS (DK) | 1989-11-02 | — | — | WO | disclosed |