Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.61 |
| ▸ | RXRB | P28702 | 10/20 | 0.61 |
| ▸ | RXRG | P48443 | 10/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9466275 | 0.83 | ALOX5 (0.50) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9522392 | 0.81 | RXRA (0.81) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL5551695 | 0.79 | RXRA (0.78) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL5547124 | 0.79 | RXRA (0.78) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL5393447 | 0.75 | RXRA (0.84) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL6501484 | 0.74 | PTGS2 (0.74) | RXRARXRBRXRGPTGS2 | |
| SCHEMBL9466056 | 0.73 | RXRA (0.55) | RXRARXRBRXRGMALT1 | |
| SCHEMBL4009771 | 0.71 | RXRA (0.57) | RXRARXRBRXRG | |
| SCHEMBL9466584 | 0.71 | RXRA (0.53) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL14445463 | 0.71 | RXRA (0.78) | RXRARXRBRXRGALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242940-A | Antiinflammatory agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-09-07 | — | — | US | disclosed |