SCHEMBL9465833

SCHEMBL9465833

Clc1ccc(C2=N[N]C=C2)s1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.39
HSD17B1 P14061 4/20 0.36
PTGS1 P23219 3/20 0.33
PTGS2 P35354 3/20 0.33
ALDH1A1 P00352 4/20 0.33
HSD17B2 P37059 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KDM1A O60341 1/20 0.32
PGR P06401 1/20 0.32
KDM4E B2RXH2 3/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
LMNA P02545 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
PPARG P37231 1/20 0.30
NCOA2 Q15596 1/20 0.30
NCOA1 Q15788 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9465935 0.78 NPC1 (0.37) PTGS1PTGS2ALDH1A1MAPTPGR
SCHEMBL9466565 0.76 SNCA (0.39) ALDH1A1MEN1KMT2AMAPTL3MBTL1
SCHEMBL9465562 0.67 CYP2A6 (0.39) CYP2A6ALDH1A1MEN1KMT2AMAPT
SCHEMBL3516703 0.66 CYP1A2 (0.39) CYP2A6L3MBTL1KDM4ESMN1; SMN2LMNA
SCHEMBL9465121 0.63 HCAR2 (0.33)
SCHEMBL144429 0.63 CYP2A6 (0.45) CYP2A6HSD17B1PTGS1PTGS2ALDH1A1
SCHEMBL9465496 0.63 HDAC8 (0.39)
SCHEMBL9466192 0.61 ALDH1A1 (0.36) ALDH1A1MAPTGAAHPGD
SCHEMBL293609 0.61 CYP2A6 (0.41) CYP2A6ALDH1A1KMT2AKDM4ESMN1; SMN2
SCHEMBL9465604 0.61 NPC1 (0.48) HSD17B1ALDH1A1HSD17B2KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5246914-A Fungicides and plant growth regulators BASF AKTIENGESELLSCHAFT (DE) 1993-09-21 US disclosed