SCHEMBL9466565

SCHEMBL9466565

Brc1ccc(C2=N[N]C=C2)s1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.39
MAPT P10636 4/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
HSD17B10 Q99714 2/20 0.38
ALOX12 P18054 2/20 0.38
ALOX15 P16050 1/20 0.38
KDM4E B2RXH2 4/20 0.36
RAB9A P51151 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
RXFP1 Q9HBX9 3/20 0.36
NPC1 O15118 2/20 0.36
ALDH1A1 P00352 2/20 0.36
PPARG P37231 2/20 0.36
NCOA2 Q15596 2/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36
NCOA1 Q15788 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9465935 0.78 NPC1 (0.37) MAPTHSD17B10KDM4ERAB9ASMN1; SMN2
SCHEMBL9465833 0.76 CYP2A6 (0.39) MAPTMEN1KMT2AKDM4ERAB9A
SCHEMBL197157 0.69 SNCA (0.50) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL9465259 0.69 CYP2A6 (0.46) MAPTMEN1KMT2AALOX15KDM4E
SCHEMBL9465056 0.68 MAPK13 (0.30) MAPK13GCGRMAPK12MAPK11MAPK14
SCHEMBL2778388 0.68 SNCA (0.61) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL498474 0.67 SNCA (0.48) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL5453288 0.67 SNCA (0.48) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL5889177 0.67 SNCA (0.48) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL5889194 0.67 SNCA (0.48) SNCAMAPTMEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5246914-A Fungicides and plant growth regulators BASF AKTIENGESELLSCHAFT (DE) 1993-09-21 US disclosed