Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9166372 | 0.89 | GRM2 (0.31) | GAAMAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9159054 | 0.89 | GAA (0.31) | GAAMAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9159027 | 0.88 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9163999 | 0.88 | ESR1 (0.36) | MAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9167118 | 0.88 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9465609 | 0.86 | CTSK (0.37) | MAPT | |
| SCHEMBL9465442 | 0.85 | TYR (0.33) | — | |
| SCHEMBL9160655 | 0.85 | ALDH1A1 (0.34) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9160934 | 0.85 | ITGB3 (0.39) | SLC6A4 | |
| SCHEMBL9467546 | 0.84 | ACACB (0.35) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204018-A | LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1993-04-20 | — | — | US | disclosed |