Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.68 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.56 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14110105 | 0.87 | PLOD2 (0.72) | PLOD2PLOD3PLOD1ALDH1A1GAA | |
| SCHEMBL29450185 | 0.86 | PLOD2 (0.66) | PLOD2PLOD3PLOD1ALDH1A1GAA | |
| SCHEMBL2638149 | 0.86 | PLOD2 (0.66) | PLOD2PLOD3PLOD1ALDH1A1GAA | |
| SCHEMBL2694778 | 0.84 | PLOD2 (0.79) | PLOD2PLOD3PLOD1ALDH1A1GAA | |
| SCHEMBL4947413 | 0.83 | PLOD2 (0.61) | PLOD2PLOD3PLOD1ALDH1A1GAA | |
| SCHEMBL29554726 | 0.82 | PLOD2 (0.89) | PLOD2PLOD3PLOD1ALDH1A1GAA | |
| SCHEMBL10320930 | 0.82 | PLOD2 (0.89) | PLOD2PLOD3PLOD1ALDH1A1GAA | |
| SCHEMBL30440488 | 0.81 | PLOD2 (1.00) | PLOD2PLOD3PLOD1ALDH1A1GAA | |
| SCHEMBL4625207 | 0.81 | PLOD2 (1.00) | PLOD2PLOD3PLOD1ALDH1A1GAA | |
| SCHEMBL6563638 | 0.81 | ALDH1A1 (0.74) | PLOD2PLOD3PLOD1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242940-A | Antiinflammatory agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-09-07 | — | — | US | disclosed |