Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9466169 | 1.00 | LCK (0.48) | LCKFYNDAOCES2CES1 | |
| SCHEMBL11340772 | 0.80 | CES2 (0.55) | LCKFYNDAOCES2CES1 | |
| SCHEMBL11340749 | 0.80 | CES2 (0.55) | LCKFYNDAOCES2CES1 | |
| SCHEMBL9466164 | 0.79 | MAPT (0.41) | LCKFYNDAOCES2CES1 | |
| SCHEMBL9466159 | 0.79 | MAPT (0.41) | LCKFYNDAOCES2CES1 | |
| SCHEMBL7270607 | 0.78 | LCK (0.59) | LCKFYNDAOCES2CES1 | |
| SCHEMBL2566022 | 0.77 | ALDH1A1 (0.51) | DAOCES2CES1ALDH1A1MAPT | |
| SCHEMBL3289274 | 0.77 | ALDH1A1 (0.51) | DAOCES2CES1ALDH1A1MAPT | |
| SCHEMBL2566020 | 0.77 | ALDH1A1 (0.51) | DAOCES2CES1ALDH1A1MAPT | |
| SCHEMBL29119462 | 0.75 | TSHR (0.46) | DAOALDH1A1MAPTTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252749-A | Binding to serotonin receptors 5HT3, 5HT1D and 5HT1B; hypotensive agents; cardiovascular and psychological disorders | ELF SANOFI (FR) | 1993-10-12 | — | — | US | disclosed |