Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9466392 | 0.77 | TRPM5 (0.43) | TRPM5TP53RECQLAADAT | |
| SCHEMBL9466426 | 0.72 | TRPM5 (0.44) | TRPM5 | |
| SCHEMBL9467001 | 0.70 | TRPM5 (0.46) | TRPM5TP53RECQLAADAT | |
| SCHEMBL7810600 | 0.69 | MTNR1A (0.43) | HTR2A | |
| SCHEMBL9178119 | 0.67 | TRPM5 (0.41) | TRPM5HTR2CHTR2AHTR2BTP53 | |
| SCHEMBL19934176 | 0.67 | AADAT (0.50) | TRPM5HTR2CHTR2AHTR2BTP53 | |
| Hydrochloric Acid SCHEMBL19925523 | 0.66 | AADAT (0.49) | TRPM5HTR2CHTR2AHTR2BTP53 | |
| SCHEMBL30666576 | 0.66 | TRPM5 (0.41) | TRPM5HTR2CHTR2AHTR2BTP53 | |
| SCHEMBL11452212 | 0.64 | TRPM5 (0.40) | TRPM5HTR2CHTR2AHTR2BTP53 | |
| SCHEMBL19899107 | 0.64 | TRPM5 (0.43) | TRPM5HTR2CHTR2AHTR2BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194437-A | Substituted with oxygen containing heterocycle, central nervous system disorders, neuroendocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |