SCHEMBL9466558

SCHEMBL9466558

Cc1ccc(S(=O)(=O)OCC[C@H](C)CCC(OCc2ccccc2)O[Si](C)(C)C(C)(C)C)cc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
LMNA P02545 2/20 0.33
AR P10275 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
GAA P10253 1/20 0.32
PKM P14618 1/20 0.32
MAPT P10636 2/20 0.32
CNR2 P34972 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
P2RX7 Q99572 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9466546 0.81 ALDH1A1 (0.38) ALDH1A1LMNAARSMN1; SMN2GAA
SCHEMBL27031879 0.77 ALDH1A1 (0.44) ALDH1A1LMNAARSMN1; SMN2GAA
SCHEMBL27032245 0.77 ALDH1A1 (0.44) ALDH1A1LMNAARSMN1; SMN2GAA
SCHEMBL1941766 0.77 ALDH1A1 (0.44) ALDH1A1LMNAARSMN1; SMN2GAA
SCHEMBL15284498 0.77 CA12 (0.38) ALDH1A1GAACYP1A2CA1CA2
SCHEMBL27248448 0.77 CA12 (0.38) ALDH1A1GAACYP1A2CA1CA2
SCHEMBL15284136 0.77 CA12 (0.38) ALDH1A1GAACYP1A2CA1CA2
SCHEMBL25321397 0.75 P2RX7 (0.46) LMNAP2RX7
SCHEMBL25321389 0.75 P2RX7 (0.46) LMNAP2RX7
SCHEMBL26782894 0.75 P2RX7 (0.46) LMNAP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5243096-A Optically active pentane derivatives and intermediates thereof, and process for manufacturing same ASAHI DENKA KOGYO K.K. (JP) 1993-09-07 US disclosed