Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 4/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29538416 | 0.87 | MTNR1B (0.48) | MTNR1BMTNR1AHTR6FFAR1PIN1 | |
| SCHEMBL1176599 | 0.85 | HTR6 (0.48) | MTNR1BMTNR1AHTR6FFAR1PIN1 | |
| SCHEMBL9466551 | 0.82 | MTNR1A (0.44) | MTNR1BMTNR1AHTR6FFAR1PIN1 | |
| SCHEMBL1470461 | 0.81 | FFAR1 (0.62) | MTNR1BMTNR1AHTR6FFAR1PRMT5 | |
| SCHEMBL7847075 | 0.81 | FFAR1 (0.62) | MTNR1BMTNR1AHTR6FFAR1PRMT5 | |
| SCHEMBL7845908 | 0.81 | FFAR1 (0.62) | MTNR1BMTNR1AHTR6FFAR1PRMT5 | |
| SCHEMBL11732903 | 0.78 | MTNR1A (0.49) | MTNR1BMTNR1AHTR6FFAR1PIN1 | |
| SCHEMBL1567103 | 0.78 | MTNR1A (0.56) | MTNR1BMTNR1AHTR6FFAR1PIN1 | |
| SCHEMBL1567606 | 0.77 | MTNR1A (0.51) | MTNR1BMTNR1AHTR6FFAR1PIN1 | |
| SCHEMBL1567241 | 0.77 | MTNR1A (0.55) | MTNR1BMTNR1AHTR6EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194437-A | Substituted with oxygen containing heterocycle, central nervous system disorders, neuroendocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |