Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181626 | 0.93 | PTGDR2 (0.39) | ALDH1A1KDM4EHTR6 | |
| SCHEMBL9466365 | 0.87 | PTGDR2 (0.40) | ALDH1A1KDM4EGAAPKM | |
| SCHEMBL9183292 | 0.84 | PREP (0.41) | ALDH1A1KDM4ELMNAMAPK1SMN1; SMN2 | |
| SCHEMBL1038534 | 0.84 | SIGMAR1 (0.43) | HTR6 | |
| SCHEMBL9178801 | 0.83 | CRBN (0.40) | ALDH1A1KDM4E | |
| SCHEMBL9467343 | 0.82 | SIGMAR1 (0.51) | — | |
| SCHEMBL9174172 | 0.81 | SIGMAR1 (0.43) | HTR6 | |
| SCHEMBL9179778 | 0.79 | HCRTR1 (0.43) | ALDH1A1MTNR1BSMN1; SMN2 | |
| SCHEMBL9466307 | 0.78 | SIGMAR1 (0.51) | — | |
| SCHEMBL9179381 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194437-A | Substituted with oxygen containing heterocycle, central nervous system disorders, neuroendocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |