Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1038534 | 0.94 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL9466307 | 0.88 | SIGMAR1 (0.51) | SIGMAR1 | |
| SCHEMBL9174172 | 0.88 | SIGMAR1 (0.43) | SIGMAR1ADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL9175467 | 0.83 | SIGMAR1 (0.40) | SIGMAR1KCNH2TMEM97HTR1A | |
| SCHEMBL9467124 | 0.82 | ALDH1A1 (0.36) | — | |
| SCHEMBL9175775 | 0.80 | SIGMAR1 (0.45) | SIGMAR1CHRM2CHRM4ABCB1CHRM5 | |
| SCHEMBL8303444 | 0.80 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL9181626 | 0.80 | PTGDR2 (0.39) | — | |
| SCHEMBL9178363 | 0.78 | SIGMAR1 (0.41) | SIGMAR1HTR1A | |
| SCHEMBL9178801 | 0.75 | CRBN (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194437-A | Substituted with oxygen containing heterocycle, central nervous system disorders, neuroendocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |