Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | GHSR | Q92847 | 1/20 | 0.51 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.51 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 2/20 | 0.49 |
| ▸ | FLT4 | P35916 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468104 | 0.86 | CA1 (0.64) | KMT2AMEN1CA1CA2ALDH1A1 | |
| SCHEMBL9483252 | 0.86 | KMT2A (0.58) | KMT2AMEN1CA1CA2ALDH1A1 | |
| SCHEMBL28113465 | 0.85 | BDKRB1 (0.63) | KMT2AMEN1CA1CA2FLT1 | |
| SCHEMBL19629833 | 0.84 | ALDH1A1 (0.62) | HDAC3HDAC6HDAC8HDAC11KMT2A | |
| SCHEMBL9483831 | 0.82 | CA12 (0.54) | KMT2AMEN1CA1CA2ALDH1A1 | |
| SCHEMBL9468106 | 0.82 | FLT1 (0.64) | KMT2AMEN1CA1CA2ALDH1A1 | |
| SCHEMBL10201044 | 0.81 | NPC1 (0.68) | HDAC3HDAC6HDAC8HDAC11KMT2A | |
| SCHEMBL343103 | 0.81 | TP53 (0.52) | KMT2AMEN1CA1CA2ALDH1A1 | |
| SCHEMBL12201959 | 0.80 | PTGS2 (0.66) | HDAC3HDAC6HDAC8HDAC11KMT2A | |
| SCHEMBL9483024 | 0.80 | MAPT (0.55) | KMT2AMEN1ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215570-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | claimed |
| EP-0365484-B1 | SULFAMOYL PHENYL UREAS | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | claimed |
| US-5215570-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |