Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468048 | 0.89 | LMNA (0.58) | TP53KMT2APKMLMNARAB9A | |
| SCHEMBL9468014 | 0.86 | PKM (0.52) | KMT2APKMCA12CA1CA2 | |
| SCHEMBL9468472 | 0.86 | TP53 (0.52) | TP53KMT2APKMCA12CA1 | |
| SCHEMBL9484600 | 0.86 | ALDH1A1 (0.56) | KMT2AMEN1LMNARAB9AALDH1A1 | |
| SCHEMBL9483282 | 0.86 | MEN1 (0.56) | TP53KMT2ACA12CA1CA2 | |
| SCHEMBL9468104 | 0.85 | CA1 (0.64) | TP53KMT2ACA12CA1CA2 | |
| SCHEMBL9466896 | 0.84 | CA12 (0.56) | TP53KMT2ACA12CA1CA2 | |
| SCHEMBL9467786 | 0.84 | FLT1 (0.67) | KMT2APKMCA1CA2CA9 | |
| SCHEMBL9467745 | 0.84 | LMNA (0.54) | TP53KMT2ACA12CA1CA2 | |
| SCHEMBL9467720 | 0.84 | CA12 (0.51) | TP53KMT2APKMCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 938 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099751-B1 | BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | claimed |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-07 | — | — | US | claimed |
| EP-2185563-B1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-08-19 | — | — | EP | claimed |
| EP-1943218-B1 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | claimed |
| US-8993782-B2 | Cis-alkoxyspirocyclic biphenyl-substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-31 | — | — | US | claimed |
| EP-2195290-B1 | HALOGEN ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-03-11 | — | — | EP | claimed |
| EP-2825547-A1 | COMBINED SYNTHESIS ROUTE FOR ETONOGESTREL AND DESOGESTREL | Merck Sharp & Dohme B.V. (NL) | 2015-01-21 | — | — | EP | claimed |
| EP-1771067-B1 | SELECTIVE INSECTICIDES BASED ON SUBSTITUTED, CYCLIC KETO-ENOLS AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2014-03-12 | — | — | EP | claimed |
| US-8629084-B2 | Iodine-phenyl-substituted cyclic cetoenols | BAYER CROPSCIENCE AG (DE) | 2014-01-14 | — | — | US | claimed |
| EP-1855529-B1 | SPIROKETAL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2013-12-18 | — | — | EP | claimed |
| US-20040132619-A1 | Selective substituted aryl ketone and safener based herbicides | BAYER CROPSCIENCE K.K. (JP) | 2004-07-08 | — | — | US | claimed |
| CN-1503626-A | Herbicidal composition containing benzoylcyclohexanediones and safeners | �Ϻ���ͨ��ѧ | 2004-06-09 | — | — | CN | claimed |
| EP-1130965-B1 | COMBINATIONS OF HERBICIDES AND SAFENERS | BAYER CROPSCIENCE GMBH (DE) | 2003-10-29 | — | — | EP | claimed |
| US-20030171220-A1 | Combinations of herbicides and safeners | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-09-11 | — | — | US | claimed |
| US-20030158039-A1 | Herbicidal compositions comprising benzoylpyrazoles and safeners | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-08-21 | — | — | US | claimed |
| US-20030078167-A1 | Herbicides comprising benzoylcyclohexanediones and safeners | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-04-24 | — | — | US | claimed |
| CN-1306395-A | Combinations of herbicides and safeners | AVENTIS CROPSCIENCE GMBH (DE) | 2001-08-01 | — | — | CN | claimed |
| US-5541148-A | USED WITH AGRICULTURAL CEREAL CROPS | CIBA-GEIGY CORPORATION (US) | 1996-07-30 | — | — | US | claimed |
| US-5215570-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | claimed |
| EP-0365484-B1 | SULFAMOYL PHENYL UREAS | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171220-A1 | Combinations of herbicides and safeners | DDT, CYP2B6, CYP2A6 | TP53 1558/4885KMT2A 470/4885PKM 2562/4885 |
| US-20030158039-A1 | Herbicidal compositions comprising benzoylpyrazoles and safeners | DDT, CYP4Z1, HDHD5 | TP53 1586/4885KMT2A 1209/4885PKM 2079/4885 |
| US-20030078167-A1 | Herbicides comprising benzoylcyclohexanediones and safeners | DDT, HPD, HDHD5 | TP53 3743/4885KMT2A 2491/4885PKM 1876/4885 |
| US-20040132619-A1 | Selective substituted aryl ketone and safener based herbicides | CYP2W1, CYP4Z1, CYP2E1 | TP53 3580/4885KMT2A 498/4885PKM 450/4885 |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | DDT, CYP4X1, CYP51A1 | TP53 3908/4885KMT2A 1264/4885PKM 1663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.