SCHEMBL9467828

SCHEMBL9467828

Ic1ccc(SSc2ccc(I)c3ccccc23)c2ccccc12

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
APOBEC3G Q9HC16 2/20 0.34
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9467929 0.85 APOBEC3G (0.34) APOBEC3GMEN1MAPTKMT2ANPSR1
SCHEMBL9467836 0.81
SCHEMBL29926858 0.81 ALDH1A1 (0.39)
SCHEMBL3193406 0.81 ALDH1A1 (0.39)
SCHEMBL5475073 0.73 CYP2A6 (0.33)
SCHEMBL11594393 0.70 IDO1 (0.65) APOBEC3GMAPT
SCHEMBL225136 0.70 CYP3A4 (0.50) APOBEC3GMEN1MAPTKMT2ANPSR1
SCHEMBL30608894 0.68 NOS1 (0.44) NPSR1
SCHEMBL1269977 0.68 NOS1 (0.44) NPSR1
SCHEMBL1949490 0.67 MEN1 (0.33) APOBEC3GMEN1MAPTKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5239052-A Heating aromatic disulfide in the presence of an aromatic halide HAY ALLAN S (CA) 1993-08-24 US disclosed
US-5177183-A Reaction of a halophenyl disulfide to form polyphenylene thioether HAY ALLAN S (CA) 1993-01-05 US disclosed