SCHEMBL9467929

SCHEMBL9467929

Ic1cccc2c(SSc3cccc4c(I)cccc34)cccc12

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
APOBEC3G Q9HC16 2/20 0.34
NOS1 P29475 1/20 0.34
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TYMS P04818 2/20 0.32
PSMD14 O00487 1/20 0.32
DYRK1A Q13627 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9467828 0.85 APOBEC3G (0.34) APOBEC3GMEN1MAPTKMT2ANPSR1
SCHEMBL9467944 0.81 NOS1 (0.32) NOS1TYMS
SCHEMBL18610396 0.81 TYMS (0.33) NOS1MEN1MAPTKMT2ANPSR1
SCHEMBL1269977 0.81 NOS1 (0.44) NOS1NPSR1TYMSDYRK1A
SCHEMBL30608894 0.81 NOS1 (0.44) NOS1NPSR1TYMSDYRK1A
SCHEMBL943060 0.73 APOBEC3G (0.46) APOBEC3GMEN1MAPTKMT2ANPSR1
SCHEMBL18242598 0.72 TYMS (0.36) NOS1NPSR1TYMSDYRK1A
SCHEMBL223523 0.70 ALDH1A1 (0.65) APOBEC3GMEN1MAPTKMT2ANPSR1
SCHEMBL943339 0.70 APOBEC3G (0.33) APOBEC3GMEN1MAPTKMT2ANPSR1
SCHEMBL22077551 0.69 NOS1 (0.37) NOS1NPSR1TYMSDYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5239052-A Heating aromatic disulfide in the presence of an aromatic halide HAY ALLAN S (CA) 1993-08-24 US disclosed
US-5177183-A Reaction of a halophenyl disulfide to form polyphenylene thioether HAY ALLAN S (CA) 1993-01-05 US disclosed