Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467445 | 0.72 | — | — | |
| SCHEMBL9466733 | 0.71 | — | — | |
| SCHEMBL21231244 | 0.70 | ALDH1A1 (0.42) | KDM4EALDH1A1GAA | |
| SCHEMBL4372931 | 0.70 | MAPKAPK2 (0.45) | — | |
| SCHEMBL10289305 | 0.70 | MAPT (0.34) | KDM4EALDH1A1GAA | |
| SCHEMBL21842818 | 0.68 | GPR84 (0.41) | ALDH1A1 | |
| SCHEMBL2210620 | 0.68 | — | — | |
| SCHEMBL2213430 | 0.67 | POLB (0.30) | GAA | |
| SCHEMBL30740608 | 0.66 | — | — | |
| SCHEMBL2240355 | 0.66 | THRA (0.34) | KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5206360-A | Bactericides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-04-27 | — | — | US | disclosed |
| US-5169843-A | Bactericides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0484030-A2 | Antibiotic C-3 cyclobutenedione substituted (1-carba)cephalosporin compounds, compositions, and methods of use thereof | Bristol-Myers Squibb Company (US) | 1992-05-06 | — | — | EP | disclosed |
| US-5106842-A | Bactericides | BRISTOL-MYERS SQUIBB CO. (US) | 1992-04-21 | — | — | US | disclosed |