Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 3/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426949 | 0.83 | LMNA (0.56) | LMNANPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11568943 | 0.77 | HCAR2 (0.48) | ADRB2ADRB1ADRB3FFAR1 | |
| SCHEMBL10233485 | 0.77 | SCD (0.44) | SCDCCNE1CDK2CDK5SMN1; SMN2 | |
| SCHEMBL14887789 | 0.75 | CCNE1 (0.44) | LMNASCDFDPSCCNE1CDK2 | |
| SCHEMBL25212455 | 0.75 | SMN1; SMN2 (0.46) | LMNACYP1A2CYP2C9CYP2C19ADRB2 | |
| SCHEMBL19647495 | 0.75 | LMNA (0.54) | LMNANPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL5835647 | 0.74 | SMN1; SMN2 (0.49) | MAPTADRB2ADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL13094326 | 0.73 | ADRB2 (0.43) | ADRB2ADRB1ADRB3SMN1; SMN2FFAR1 | |
| SCHEMBL12868670 | 0.73 | SLC6A3 (0.46) | SCDADRB2ADRB1ADRB3FFAR1 | |
| SCHEMBL22619460 | 0.72 | CDK2 (0.53) | LMNANPC1RAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258396-A | Thiazole derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0511021-A1 | Novel thiazole derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-10-28 | — | — | EP | disclosed |