Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.50 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3869051 | 0.75 | MEN1 (0.55) | KMT2AMEN1ANO1ANO2ALDH1A1 | |
| SCHEMBL1010851 | 0.74 | KMT2A (0.67) | KMT2AHPGDGAALMNAMAPT | |
| SCHEMBL3870178 | 0.73 | HSD17B10 (0.68) | NPSR1KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL7135010 | 0.72 | MEN1 (0.54) | NPSR1KMT2AMEN1HPGDANO1 | |
| SCHEMBL9926532 | 0.71 | HTT (0.54) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL967886 | 0.70 | L3MBTL1 (0.51) | NPSR1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL29246641 | 0.70 | GAA (0.60) | KMT2AMEN1HPGDALDH1A1GAA | |
| SCHEMBL3876888 | 0.70 | MEN1 (0.51) | NPSR1KMT2AMEN1ANO1ANO2 | |
| SCHEMBL10864958 | 0.70 | CYP3A4 (0.61) | KMT2AMEN1ANO1ANO2ALDH1A1 | |
| SCHEMBL20738591 | 0.69 | SETDB1 (0.53) | KMT2AMEN1ANO1ANO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219857-A | Method of treating cognitive and related neural behavioral problems | AMERICAN CYANAMID COMPANY (US) | 1993-06-15 | — | — | US | disclosed |