Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | SNCA | P37840 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3086944 | 0.81 | ADORA3 (0.49) | GAASNCANPC1RAB9AMAPT | |
| SCHEMBL28299926 | 0.78 | NPC1 (0.57) | GAANPC1RAB9AMTNR1BNQO2 | |
| SCHEMBL29356619 | 0.77 | ALDH1A1 (0.77) | GAANPC1RAB9ANAMPTALDH1A1 | |
| SCHEMBL6270935 | 0.77 | ALDH1A1 (0.77) | GAANPC1RAB9ANAMPTALDH1A1 | |
| SCHEMBL3784241 | 0.77 | DNMT3A (0.80) | NPC1RAB9ADNMT3A | |
| SCHEMBL7433243 | 0.75 | FFAR1 (0.50) | GAAALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL330382 | 0.75 | DNMT3A (0.55) | GAADNMT3ASMN1; SMN2 | |
| SCHEMBL29111414 | 0.75 | MTNR1A (0.65) | NPC1RAB9AMTNR1BNQO2MTNR1A | |
| SCHEMBL5724399 | 0.75 | NPC1 (0.64) | GAANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5753081 | 0.74 | NPC1 (0.79) | GAANPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823021-A | NLRP3 small molecule inhibitor and preparation method and application thereof | 复旦大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-118255698-A | Sulfonamide compound and preparation method and application thereof | 海南大学 | 2024-06-28 | — | — | CN | disclosed |