Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 3/20 | 0.43 |
| ▸ | JAK1 | P23458 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2796621 | 0.86 | ALDH1A1 (1.00) | ALDH1A1NPSR1KMT2ANOTUMAGTR1 | |
| SCHEMBL27879680 | 0.81 | ALDH1A1 (0.67) | ALDH1A1NPSR1KMT2ANOTUMTSHR | |
| SCHEMBL12615992 | 0.76 | ALDH1A1 (0.68) | ALDH1A1NPSR1KMT2ANOTUMTSHR | |
| SCHEMBL436604 | 0.75 | ALDH1A1 (0.58) | ALDH1A1NPSR1KMT2ANOTUM | |
| Fluoride SCHEMBL28811107 | 0.74 | ALDH1A1 (0.56) | ALDH1A1NPSR1KMT2ANOTUM | |
| Hydrochloric Acid SCHEMBL27602135 | 0.74 | ALDH1A1 (0.56) | ALDH1A1NPSR1KMT2ANOTUM | |
| SCHEMBL9153968 | 0.73 | ALDH1A1 (0.51) | ALDH1A1NPSR1KMT2ANOTUMJAK2 | |
| SCHEMBL4317005 | 0.72 | ALDH1A1 (0.44) | ALDH1A1NPSR1KMT2ANOTUMTSHR | |
| SCHEMBL82595 | 0.71 | MAPT (0.69) | ALDH1A1KMT2ANOTUM | |
| SCHEMBL3656681 | 0.71 | ALDH1A1 (0.68) | ALDH1A1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210211-A | 4-(1H-PYRROL-1-YL) IMIDAZOLES WITH ANGIOTENSION II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1993-05-11 | — | — | US | disclosed |