⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468672 | 0.88 | — | — | |
| SCHEMBL9468245 | 0.88 | — | — | |
| SCHEMBL9474267 | 0.81 | — | — | |
| SCHEMBL9156443 | 0.81 | — | — | |
| SCHEMBL9468578 | 0.78 | AGTR1 (0.40) | — | |
| SCHEMBL9308910 | 0.76 | GP6 (0.46) | — | |
| SCHEMBL9481512 | 0.74 | — | — | |
| SCHEMBL9480825 | 0.73 | PTGER1 (0.42) | — | |
| SCHEMBL9150272 | 0.71 | AGTR1 (0.44) | — | |
| SCHEMBL9151903 | 0.71 | GP6 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252593-A | Hypotensive agents, cognition activators | GLAXO GROUP LIMITED (GB) | 1993-10-12 | — | — | US | disclosed |
| EP-0514217-A1 | Antihypertensive benzofuran derivatives carrying 4-pyrazolylmethyl substituents | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |