Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 5/20 | 0.53 |
| ▸ | OGG1 | O15527 | 1/20 | 0.52 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | AOC2 | O75106 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468858 | 0.85 | KDM4E (0.54) | KDM4EALDH1A1HPGDTDP1HTR1B | |
| SCHEMBL9468859 | 0.85 | KDM4E (0.54) | KDM4EALDH1A1HPGDTDP1HTR1B | |
| SCHEMBL29483377 | 0.85 | AOC2 (0.64) | KDM4EALDH1A1HPGDTDP1HTR1B | |
| SCHEMBL1282141 | 0.85 | AOC2 (0.64) | KDM4EALDH1A1HPGDTDP1HTR1B | |
| SCHEMBL1282142 | 0.85 | AOC2 (0.64) | KDM4EALDH1A1HPGDTDP1HTR1B | |
| SCHEMBL9468836 | 0.74 | AGXT (0.54) | KDM4EHPGDTDP1AOC2MAOA | |
| SCHEMBL9700908 | 0.73 | HTR1B (0.57) | KDM4EALDH1A1HPGDTDP1HTR1B | |
| SCHEMBL6651174 | 0.73 | HTR1B (0.71) | KDM4EALDH1A1HPGDTDP1HTR1B | |
| SCHEMBL3253891 | 0.72 | KDM4E (0.72) | KDM4EALDH1A1HPGDTDP1HTR1B | |
| SCHEMBL1614613 | 0.72 | KDM4E (0.72) | KDM4EALDH1A1HPGDTDP1HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252608-A | Preventing the abnormal deposition of collagen by administering a halogenated allyl amines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-12 | — | — | US | claimed |