Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 4/20 | 0.64 |
| ▸ | MAOA | P21397 | 4/20 | 0.64 |
| ▸ | MAOB | P27338 | 4/20 | 0.64 |
| ▸ | DAO | P14920 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.54 |
| ▸ | HTR1B | P28222 | 2/20 | 0.53 |
| ▸ | OGG1 | O15527 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282141 | 1.00 | AOC2 (0.64) | AOC2MAOAMAOBDAOKDM4E | |
| SCHEMBL29483377 | 1.00 | AOC2 (0.64) | AOC2MAOAMAOBDAOKDM4E | |
| SCHEMBL9468858 | 0.85 | KDM4E (0.54) | AOC2MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL9468859 | 0.85 | KDM4E (0.54) | AOC2MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL9468614 | 0.85 | KDM4E (0.54) | AOC2MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL3505391 | 0.78 | AOC2 (0.68) | AOC2MAOAMAOBDAOKDM4E | |
| SCHEMBL8248653 | 0.76 | MAOB (0.60) | AOC2MAOAMAOBDAOALDH1A1 | |
| SCHEMBL24147679 | 0.75 | MAOA (0.62) | AOC2MAOAMAOBDAOKDM4E | |
| SCHEMBL3505446 | 0.75 | MAOB (0.62) | AOC2MAOAMAOBDAOAOC3 | |
| SCHEMBL9468678 | 0.74 | AOC2 (0.69) | AOC2MAOAMAOBDAOAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252608-A | Preventing the abnormal deposition of collagen by administering a halogenated allyl amines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-12 | — | — | US | claimed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-113227089-B | Substituted 6-azabenzimidazole compounds as HPK1 inhibitors | 吉利德科学公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-113773387-B | PD-L1 antibodies and uses thereof | 天境生物科技(上海)有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118221646-A | PD-1/PD-L1 inhibitors | 吉利德科学公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118201941-A | CD73 compounds | 吉利德科学公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-118178645-A | Combination therapy for the treatment of myelodysplastic syndrome and acute myeloid leukemia | 四十七公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-118139858-A | Pyrazin-3 (2H) -one derivatives | 吉利德科学公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-118084940-A | PD-1/PD-L1 inhibitors | 吉利德科学公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117964757-A | Antibodies and fusion proteins that bind CCR8 and uses thereof | 吉利德科学公司 | 2024-05-03 | — | — | CN | disclosed |
| EP-2185198-A1 | LOX AND L0XL2 INHIBITORS AND USES THEREOF | Arresto Biosciences, Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| EP-2182981-A2 | METHODS AND COMPOSITIONS FOR TREATMENT AND DIAGNOSIS OF FIBROSIS, TUMOR INVASION, ANGIOGENESIS, AND METASTASIS | Arresto Biosciences, Inc. (US) | 2010-05-12 | — | — | EP | disclosed |
| CN-101489394-A | Methods and compositions for the in vivo treatment and prevention of tumor metastasis | UNIV LELAND STANFORD JUNIOR (US) | 2009-07-22 | — | — | CN | disclosed |
| US-20090104201-A1 | METHODS AND COMPOSITIONS FOR TREATMENT AND DIAGNOSIS OF FIBROSIS, TUMOR INVASION, ANGIOGENESIS, AND METASTASIS | GILEAD BIOLOGICS, INC. | 2009-04-23 | — | — | US | disclosed |
| WO-2009035791-A1 | LOX AND L0XL2 INHIBITORS AND USES THEREOF | ARRESTO BIOSCIENCES (US) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009017833-A2 | METHODS AND COMPOSITIONS FOR TREATMENT AND DIAGNOSIS OF FIBROSIS, TUMOR INVASION, ANGIOGENESIS, AND METASTASIS | ARRESTO BIOSCIENCES (US) | 2009-02-05 | — | — | WO | disclosed |
| EP-2010224-A2 | METHOD AND COMPOSITION FOR TREATING AND PREVENTING TUMOR METASTASIS IN VIVO | The Board of Trustees of The Leland Stanford Junior University (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007126457-A2 | METHOD AND COMPOSITION FOR TREATING AND PREVENTING TUMOR METASTASIS IN VIVO | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2007-11-08 | — | — | WO | disclosed |
| US-20070225242-A1 | Method and composition for treating and preventing tumor metastasis in vivo | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2007-09-27 | — | — | US | disclosed |
| US-20070021365-A1 | Inhibition of Lysyl oxidase for treating tumor growth and diagnostics relating thereto | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2007-01-25 | — | — | US | disclosed |