Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468564 | 0.85 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL947943 | 0.85 | NPC1 (0.41) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL466590 | 0.81 | NPC1 (0.47) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL7172078 | 0.79 | NPC1 (0.48) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL4357048 | 0.79 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL574153 | 0.77 | NPC1 (0.46) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL9183011 | 0.76 | NPC1 (0.58) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL11620211 | 0.75 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL11615531 | 0.75 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL28368729 | 0.75 | NPC1 (0.44) | NPC1RAB9ALMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264406-A | Alkali or alkaline metal hypophosphites with amines | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1993-11-23 | — | — | US | disclosed |
| US-5264541-A | Nylon 6 synthesis with water, alkali metal hypophoshite catalyst and amine cocatalyst | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1993-11-23 | — | — | US | disclosed |
| US-5260246-A | Comprising alkali metal/alkaline earth hypophosphites and amine or benzotriazole cocatalysts | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1993-11-09 | — | — | US | disclosed |