SCHEMBL574153

SCHEMBL574153

CCC(c1ccccc1)c1cc(C(CC)c2ccccc2)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.46
RAB9A P51151 5/20 0.46
LMNA P02545 2/20 0.46
CYP2C9 P11712 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
CYP2C19 P33261 1/20 0.44
POLB P06746 2/20 0.41
KDM4E B2RXH2 4/20 0.41
HKDC1 Q2TB90 1/20 0.38
HPGD P15428 3/20 0.36
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP17A1 P05093 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
NPSR1 Q6W5P4 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
BCHE P06276 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2590802 0.89 NPC1 (0.42) NPC1RAB9ALMNACYP2C9CYP1A2
SCHEMBL16540651 0.84 CYP3A4 (0.47) NPC1RAB9ALMNACYP2C9CYP1A2
SCHEMBL11620211 0.82 NPC1 (0.45) NPC1RAB9ALMNATSHRPOLB
SCHEMBL947943 0.81 NPC1 (0.41) NPC1RAB9ALMNACYP2C9CYP1A2
SCHEMBL8777471 0.81 NPC1 (0.49) NPC1RAB9ALMNATSHRPOLB
SCHEMBL466590 0.79 NPC1 (0.47) NPC1RAB9ALMNATSHRPOLB
SCHEMBL9468655 0.77 NPC1 (0.45) NPC1RAB9ALMNATSHRPOLB
SCHEMBL4357048 0.77 NPC1 (0.50) NPC1RAB9ALMNACYP1A2CYP3A4
SCHEMBL28368729 0.76 NPC1 (0.44) NPC1RAB9ALMNAPOLBKDM4E
SCHEMBL13373933 0.76 NPC1 (0.44) NPC1RAB9ALMNATSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090061-A1 ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION JP LABORATORIES, INC. (US) 2025-05-01 WO claimed
EP-3152257-A1 THERMOPLASTIC COMPOSITION AND LASER-WELDED ARTICLE SABIC Global Technologies B.V. (NL) 2017-04-12 EP claimed
EP-3079904-A1 NON-YELLOWING GLASS LAMINATE STRUCTURE Corning Incorporated (US) 2016-10-19 EP claimed
WO-2015186015-A1 THERMOPLASTIC COMPOSITION AND LASER-WELDED ARTICLE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-12-10 WO claimed
WO-2015088866-A1 NON-YELLOWING GLASS LAMINATE STRUCTURE CORNING INCORPORATED (US) 2015-06-18 WO claimed
EP-2814887-A1 FLAME-RETARDANT HALOGEN-FREE POLY(PHENYLENE ETHER) COMPOSITIONS SABIC Innovative Plastics IP B.V. (NL) 2014-12-24 EP claimed
WO-2013120306-A1 FLAME-RETARDANT HALOGEN-FREE POLY(PHENYLENE ETHER) COMPOSITIONS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-08-22 WO claimed
EP-2052406-A2 ACTIVE MATRIX DISPLAYS AND OTHER ELECTRONIC DEVICES HAVING PLASTIC SUBSTRATES Koninklijke Philips Electronics N.V. (NL) 2009-04-29 EP claimed
WO-2008018026-A2 ACTIVE MATRIX DISPLAYS AND OTHER ELECTRONIC DEVICES HAVING PLASTIC SUBSTRATES KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2008-02-14 WO claimed
WO-2004085526-A1 PROTECTIVE COATINGS FOR MICROPOROUS SHEETS PPG INDUSTRIES OHIO INC. (US) 2004-10-07 WO claimed
EP-3452822-B1 A TIME-TEMPERATURE INDICATOR BASED ON INCREASED THERMAL REACTIVITY OF A DIACETYLENE UPON MELT RECRYSTALLIZATION JP LABORATORIES (US) 2026-04-01 EP disclosed
WO-2024018021-A1 FRAGRANCED COMPOSITION COMPRISING AT LEAST ONE SULFUR-COMPRISING ANTIOXIDANT COMPOUND, AT LEAST ONE ORGANIC UV SCREENING AGENT AND AT LEAST ONE FRAGRANCING SUBSTANCE. L'OREAL (FR) 2024-01-25 WO disclosed
US-11639413-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2023-05-02 US disclosed
EP-4165134-A1 FLUOROSILICONE POLYMERS, COMPOSITIONS, AND USES THEREOF ForSight Vision6, Inc. (US) 2023-04-19 EP disclosed
EP-3994192-A1 RESISTANT 2K-PUR COATINGS Covestro Intellectual Property GmbH & Co. KG (DE) 2022-05-11 EP disclosed
US-20030063237-A1 Polarizer protection film SEKISUI CHEMICAL CO., LTD. (JP) 2003-04-03 US disclosed
EP-1169396-A1 HIGH SOLIDS CLEAR COATING COMPOSITION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-01-09 EP disclosed
EP-1080258-A1 PROCESS FOR MAKING LOAD LIMITING YARN AlliedSignal Inc. (US) 2001-03-07 EP disclosed
WO-2000055263-A1 HIGH SOLIDS CLEAR COATING COMPOSITION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-09-21 WO disclosed
WO-1999061687-A1 PROCESS FOR MAKING LOAD LIMITING YARN ALLIEDSIGNAL INC. (US) 1999-12-02 WO disclosed