Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468724 | 0.89 | L3MBTL1 (0.38) | PLA2G4BTDP1L3MBTL1 | |
| SCHEMBL15155730 | 0.86 | PPARG (0.47) | DHFR | |
| SCHEMBL11942311 | 0.79 | IDO1 (0.38) | — | |
| SCHEMBL31139336 | 0.77 | IDO1 (0.33) | TSHR | |
| SCHEMBL649009 | 0.77 | PLA2G4B (0.45) | PLA2G4BTSHRTDP1L3MBTL1 | |
| SCHEMBL15155711 | 0.77 | MAPK1 (0.43) | TSHR | |
| Fluoride Ion SCHEMBL31385474 | 0.77 | DHFR (0.44) | PLA2G4BGGPS1DHFRTSHR | |
| SCHEMBL9479894 | 0.77 | PLA2G4B (0.47) | PLA2G4BGGPS1TSHRTDP1L3MBTL1 | |
| SCHEMBL9468805 | 0.77 | PLA2G4B (0.44) | PLA2G4BGGPS1TSHRTDP1L3MBTL1 | |
| SCHEMBL2560206 | 0.76 | L3MBTL1 (0.47) | TSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238832-A | Lipoxygenase inhibitors | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1993-08-24 | — | — | US | disclosed |