SCHEMBL671994

SCHEMBL671994

CC(C)c1ccc(C(C)C)c(-c2ccc(O)cc2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.46
PTGS1 P23219 1/20 0.46
CACNA1C Q13936 1/20 0.46
ESR1 P03372 5/20 0.43
ESR2 Q92731 3/20 0.43
PDCD1 Q15116 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
LMNA P02545 2/20 0.42
APP P05067 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
HIF1A Q16665 2/20 0.40
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
ALOX12 P18054 1/20 0.40
HTT P42858 1/20 0.40
RNASEH1 O60930 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10398162 0.91 ESR2 (0.42) TRPA1PTGS1CACNA1CESR1ESR2
SCHEMBL27519877 0.86 ESR1 (0.44) TRPA1ESR1ESR2LMNACA1
SCHEMBL7094188 0.85 APP (0.45) TRPA1PTGS1CACNA1CESR1ESR2
SCHEMBL2868070 0.85 LMNA (0.50) TRPA1PTGS1CACNA1CESR1ESR2
SCHEMBL29634557 0.85 LMNA (0.50) TRPA1PTGS1CACNA1CESR1ESR2
SCHEMBL9468971 0.84 ANPEP (0.44) TRPA1PTGS1ESR1ESR2LMNA
SCHEMBL3654907 0.83 ALDH1A1 (0.44) TRPA1PTGS1CACNA1CLMNACYP3A4
SCHEMBL28064838 0.83 LMNA (0.59) TRPA1PTGS1CACNA1CESR1ESR2
SCHEMBL28000746 0.81 TRPA1 (0.55) TRPA1ESR1ESR2LMNACHRM1
SCHEMBL27675692 0.81 LMNA (0.42) TRPA1PTGS1CACNA1CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 556 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117500859-A Oligoesters comprising resorcinol and isophthalic acid and/or terephthalic acid, corresponding polyester carbonates and their preparation 科思创德国股份有限公司 2024-02-02 CN claimed
CN-109563632-B Electrochemical purification of chloride-containing process solutions 科思创德国股份有限公司 2021-09-28 CN claimed
CN-105980476-B Fiber-reinforced resin composite and method for producing same 波音公司 2019-12-10 CN claimed
CN-105980476-A Fiber-reinforced resin composites and methods of making the same 波音公司 2016-09-28 CN claimed
CN-1997698-B Polyester compositions flame-retarded with halogen-free additives ITALMATCH CHEMICALS SPA 2013-01-09 CN claimed
CN-1997698-A Polyester compositions flame-retarded with halogen-free additives ITALMATCH CHEMICALS SPA (IT) 2007-07-11 CN claimed
CN-1488664-A Vibration damping material composition 株式会社泰特克斯 2004-04-14 CN claimed
CN-114729179-B Flame retardant polycarbonate-polyester blends 科思创德国股份有限公司 2024-07-05 CN disclosed
CN-118284666-A Thermoplastic mixture 巴斯夫欧洲公司 2024-07-02 CN disclosed
CN-118251294-A Method for producing pellets of flame-retardant polycarbonate resin composition 三菱工程塑料株式会社 2024-06-25 CN disclosed
CN-114746495-B Method for producing masterbatches and moulding compounds with improved properties 科思创德国股份有限公司 2024-06-11 CN disclosed
CN-114761476-B Method for producing molding materials with improved surface properties 科思创德国股份有限公司 2024-06-11 CN disclosed
CN-114650915-B Layer structure with modified structure and production thereof 科思创德国股份有限公司 2024-05-31 CN disclosed
CN-1041606-A The mixture of special polycarbonates and other thermoplastics elastomer-formings BAYER AG (DE) 1990-04-25 CN disclosed
EP-0355926-A2 Alkenyl-modified polyimides Technochemie GmbH - Verfahrenstechnik (DE) 1990-02-28 EP disclosed
EP-0353559-A1 Hydrolytically stable polycarbonate compositions MILES INC. (US) 1990-02-07 EP disclosed
EP-0311871-A2 Coextrusion structures MILES INC. (US) 1989-04-19 EP disclosed
EP-0275991-A2 Thermoplastic resin composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1988-07-27 EP disclosed
CN-85103045-A Laminated foil 1986-10-15 CN disclosed
US-4594204-A Process for annealing thermoplastically-shaped plastics parts BAYER AKTIENGESELLSCHAFT (DE) 1986-06-10 US disclosed