SCHEMBL9469052

SCHEMBL9469052

O=C1OC(=O)c2cc(Oc3cc4c(cc3F)C(=O)OC4=O)c(F)cc21

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 1/20 0.33
INPPL1 O15357 1/20 0.31
PTGS2 P35354 1/20 0.31
TYMS P04818 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9469215 0.89 TYMS (0.32) ALOX15TDP1TYMS
SCHEMBL9638481 0.84 MAOA (0.42) ALOX15TDP1ALDH1A1
SCHEMBL29441718 0.81 ALOX15 (0.48) ALOX15TDP1ALDH1A1TYMS
SCHEMBL652925 0.81 ALOX15 (0.48) ALOX15TDP1ALDH1A1TYMS
SCHEMBL13104456 0.71 GPR3 (0.40) ALOX15TDP1ALDH1A1PTGS2TYMS
SCHEMBL854455 0.71 ALOX15 (0.39) ALOX15TDP1ALDH1A1TYMS
SCHEMBL855016 0.71 TDP1 (0.39) ALOX15TDP1ALDH1A1PTGS2TYMS
SCHEMBL9743354 0.71 ALOX15 (0.34) ALOX15TDP1ALDH1A1
SCHEMBL2928543 0.70 CYP3A4 (0.53) ALOX15TDP1
SCHEMBL29557279 0.70 CYP3A4 (0.53) ALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0398206-A1 Dioxydiphthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1990-11-22 EP claimed
US-4943642-A POLYMER INTERMEDIATES, CURING AGENTS OCCIDENTAL CHEMICAL CORPORATION (US) 1990-07-24 US claimed
US-9248413-B2 Gas separation composite membrane and method of producing the same, and gas separating module, gas separation apparatus and gas separation method using the same FUJIFILM CORPORATION (JP) 2016-02-02 US disclosed
US-9248413-B2 Gas separation composite membrane and method of producing the same, and gas separating module, gas separation apparatus and gas separation method using the same FUJIFILM CORPORATION (JP) 2016-02-02 US disclosed
US-20140130667-A1 GAS SEPARATION COMPOSITE MEMBRANE AND METHOD OF PRODUCING THE SAME, AND GAS SEPARATING MODULE, GAS SEPARATION APPARATUS AND GAS SEPARATION METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2014-05-15 US disclosed
US-20140130667-A1 GAS SEPARATION COMPOSITE MEMBRANE AND METHOD OF PRODUCING THE SAME, AND GAS SEPARATING MODULE, GAS SEPARATION APPARATUS AND GAS SEPARATION METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2014-05-15 US disclosed
US-5185451-A Bis-imides of dioxydiphthalic acid OCCIDENTAL CHEMICAL CORPORATION (US) 1993-02-09 US disclosed
US-5166404-A Dioxydiphthalic acid esters OCCIDENTAL CHEMICAL CORPORATION (US) 1992-11-24 US disclosed
US-5101006-A Polyimides and copolyimides based on halo-oxydiphthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1992-03-31 US disclosed
US-5089631-A Intermediate for polyimides OCCIDENTAL CHEMICAL CORPORATION (US) 1992-02-18 US disclosed
US-5003086-A Etherification, dehalogenation, cyclization of dihalophthalic anhydride to form monomers for polyimides OCCIDENTAL CHEMICAL CORPORATION (US) 1991-03-26 US disclosed
EP-0398206-A1 Dioxydiphthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1990-11-22 EP disclosed
US-4943642-A POLYMER INTERMEDIATES, CURING AGENTS OCCIDENTAL CHEMICAL CORPORATION (US) 1990-07-24 US disclosed